1/5/2024 0 Comments Beacon design![]() When using PCR, the number of molecules doubles each step, therefore it requires about 20 cycles to amplify the template to a million-fold( 14). The NASBA process requires fewer cycle than polymerase chain reaction (PCR) to yield a desired amplification. It is an isothermal process and therefore no advanced equipment such as thermal cycler is required( 14). In this technique RNA is amplified to a billion fold in around two hours ( Fig. NASBA was selected since it is a simple and rapid alternative for nucleic acid amplification in case of RNA viruses. A number of platforms of isothermal nucleic acid amplification have been developed and introduced in the past 18 years ( 11, 12). ![]() In this respect multiplex assays are developed to reduce the cost as well as running time ( 1, 7– 10). However, molecular diagnostic technology has a major disadvantage namely high expense ( 1, 7). ![]() In order to reduce this residual risk, application of molecular techniques is recommended and is in use in several countries. Therefore, although sensitive serological tests have been developed effectively and successfully, there is still a residual risk of viral infection, due to the possibility of the HIV or HCV transmission either during the so-called window period, when viremia precedes seroreactivity, or in the presence of different viral serotypes, where the serological tests may be ineffective ( 5– 7). However, during a window period of these viruses when most serological tests are negative, infection cannot be detected in donors with newly acquired infection. Approaches to reduce transmission of these blood-borne agents from donor to recipient are stringent donor selection and performing screening tests to detect anti-HIV and anti-HCV seroreactivity in donors ( 5, 6). In all these ways, we work to lessen our environmental footprint and make the built environment better and more environmentally sensitive than when we found it.Human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) can transmit through common routes such as mother to child in pregnant women, injection drug abuse, and blood or blood products ( 1– 4). As housing managers, we monitor energy use, limit the amount of chemicals we use in landscaping, and maintain our developments to maximize useful life. Through our design decisions, we work to encourage healthy living, reduce our residents’ utility bills, minimize environmental impacts, and increase environmental awareness. When we start new developments, we explore – and typically pursue – building to the Passive House standard, in which buildings consume minimal energy for their heating, cooling, and lighting needs. Since 2008, almost all of Beacon’s new developments have been LEED- or NGBS-certifiable. Through thoughtful design, Beacon Concepts aims to inspire resident pride, create spaces for healthy living, and encourage community connections.īeacon is committed to staying at the cutting edge of green building. The Beacon Concepts team believes well-designed spaces should be available to all incomes and is particularly skilled at high impact design interventions sensitive to budget constraints. Led by Mercedes Farrando, Beacon Concepts incorporates the principles of high-end design into affordable and mixed-income housing. ![]() ![]() Beacon Concepts is our in-house design department that works in conjunction with our third-party architectural firms to ensure every design is sustainable, functional, and beautiful at each Beacon development. ![]()
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